Medeama SC will look for their first win in five games as the Ghana Premier League (GPL) continues with the Matchday 25 fixtures this weekend.
The leaders will welcome Hohoe United to the TnA Stadium, Tarkwa on Sunday as they look to preserve their one-point lead at the top of the stairs.
The action this weekend in the Ghanaian top-flight starts at Abrankese-Kumasi on Friday when Nations FC hosts Bechem United.
Two matches will be played on Saturday, with Berekum Chelsea away to Vision FC at the Nii Adjei Kraku II Sports Complex, Tema New Town.
FC Samartex will return home to play Dreams FC at the Nsenkyire Sports Arena, Samreboi.
Asante Kotoko faces another stern test on Sunday when they travel to Tamale to face the might of Karela United at the Aliu Mahama Sports Stadium.
Accra Hearts of Oak will look for their first win in three matches when they welcome Basake Holy Stars to the University of Ghana Stadium, Legon.
Aduana FC will be home to bottom side Eleven Wonders at the Nana Agyemang Badu I Park, Dormaa-Ahenkroh.
Reigning champions Bibiani Gold Stars will travel to the Wenchi Sports Stadium to play Young Apostles.
Heart of Lions will look for some respite when they host Swedru All Blacks at the Kpando Sports Stadium.